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See also Warning section.This medication is used to help relieve moderate to moderately severe pain. Tramadol is similar to opioid analgesics. It works in the brain to change how your body feels and responds to pain.

What side effects can this medication cause?

Tramadol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
sleepiness
difficulty falling asleep or staying asleep
headache
nervousness
uncontrollable shaking of a part of the body
muscle tightness
changes in mood
heartburn or indigestion
dry mouth

Usual Adult Dose for Chronic Pain:

Extended-Release (ER):
18 years or older (tramadol-naive): 100 mg orally once a day
-Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions
-Maximum Dose: 300 mg/day

For patients CURRENTLY receiving Immediate-Release (IR) Tramadol:
Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day

Conversion from other Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy
-Initial dose: 100 mg ER orally once a day
-Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions
-Maximum Dose:

Key facts

  • The most common side effects of tramadol are feeling sick and dizzy.
  • It’s possible to become addicted to tramadol, but your doctor will explain how to reduce the risks of becoming addicted.
  • If you need to take tramadol for more than a few weeks, your treatment plan may include details of how and when to stop taking this medicine.
  • It’s best not to drink alcohol with tramadol as you’re more likely to get side effects like feeling sleepy.
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